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non-linear model (continuous hinge function, segmental regression lines with gentle connection, least squares fit)  (GraphPad Software Inc)


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    GraphPad Software Inc non-linear model (continuous hinge function, segmental regression lines with gentle connection, least squares fit)
    Non Linear Model (Continuous Hinge Function, Segmental Regression Lines With Gentle Connection, Least Squares Fit), supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/linear+regression+model+function/linear+model/pmc11575207-356-17-32
    Average 90 stars, based on 1 article reviews
    non-linear model (continuous hinge function, segmental regression lines with gentle connection, least squares fit) - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Enzyme-linked Immunosorbent Assay:

    Article Title: N-halamine polyelectrolytes used for preparation of antibacterial polypropylene nonwoven fabrics and study on their basal cytotoxicity and mutagenicity
    Article Snippet: Polymeric N-halamine precursors, cationic poly((3-acrylamidopropyl) trimethylammonium chloride) (CHP) and anionic poly(2-acrylamido-2-methylpropane sulfonic acid sodium salt) (AHP), were synthesized and coated onto polypropylene nonwoven fabrics via eco-friendly dipping and spraying methods.. The successful coatings were characterized by EDS analysis.. After exposure to diluted sodium hypochlorite solution, the coatings became biocidal.

    Article Title: Anti-complement factor BB antibodies and uses thereof
    Article Snippet: Data from the ELISA were analyzed using the XY plotting function and 4-Parameter Logistic (4PL) linear regression function in GraphPad Prism software to determine the amount of free chimeric M10 or chimeric M4 present at each time point after dosing.

    Article Title: Expanded genome and proteome reallocation in a novel, robust Bacillus coagulans strain capable of utilizing pentose and hexose sugars
    Article Snippet: Optimal growth temperatures on various sugars were determined by fitting maximum growth rate versus temperature with a non-linear model (continuous hinge function, segmental regression lines with gentle connection, least squares fit) using GraphPad Prism v10.2.3.

    Article Title: In Vivo ; In Vitro Interaction of Silver Nanoparticles with Leucine Aminopeptidase from Human and Plasmodium falciparum .
    Article Snippet: There is increasing requirement for the development of new drug protocols against malaria, a fatal disease caused by the lethal parasite Plasmodium falciparum.. Leucine aminopeptidase (PfLAP) of Plasmodium falciparum, is being pursued as a promising target for the discovery of novel antimalarials.. The effects of silver nanoparticles (AgNPs) against P. falciparum leucine amino-peptidase (PfLAP) and the human homolog (HsLAP) were compared.

    Article Title: New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity.
    Article Snippet: Please cite this article as: C. Manera, A.M. Malfitano, T. Parkkari, V. Lucchesi, S. Carpi, F. Stefano, S. Bertini, C. Laezza, A. Ligresti, G. Saccomanni, J.R. Savinainen, E. Ciaglia, S. Pisanti, P. Gazzerro, V. Di Marzo, P. Nieri, M. Macchia, M. Bifulco, New quinoloneand 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity, European Journal of Medicinal Chemistry (2015), doi: 10.1016/j.ejmech.2015.04.034.

    Article Title: Transmitter self-regulation by extracellular glutamate in fresh human cortical slices.
    Article Snippet: Glutamate is thought to be the most important excitatory neurotransmitter in the CNS, while glutamine predominantly serves as a precursor and metabolite in the glutamate–glutamine cycle.. To verify the interaction between intrinsic extracellular glutamate, y-aminobutyric acid (GABA) levels and glial glutamine outflow in human tissue, fresh brain slices from human frontal cortex were incubated in superfusion chambers in vitro.. Human neocortical tissue was obtained during surgical treatment of subcortical brain tumors.

    Article Title: Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity
    Article Snippet: The concentration producing 50% inhibition (IC50) was determined by non-linear regression function PRISM 6, Version 6.01 (GraphPad Prism6 ® Software Inc., La Jolla, CA, United States).

    Article Title: The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation
    Article Snippet: ATPase reactions were carried out with increasing concentrations of ATP (12.5, 25, 50, 100, 200, 400, 800, 1600 μM) and ATPase rates were analyzed with the Michaelis-Menten non-linear regression function in GraphPad Prism.

    Software:

    Article Title: N-halamine polyelectrolytes used for preparation of antibacterial polypropylene nonwoven fabrics and study on their basal cytotoxicity and mutagenicity
    Article Snippet: Polymeric N-halamine precursors, cationic poly((3-acrylamidopropyl) trimethylammonium chloride) (CHP) and anionic poly(2-acrylamido-2-methylpropane sulfonic acid sodium salt) (AHP), were synthesized and coated onto polypropylene nonwoven fabrics via eco-friendly dipping and spraying methods.. The successful coatings were characterized by EDS analysis.. After exposure to diluted sodium hypochlorite solution, the coatings became biocidal.

    Article Title: Anti-complement factor BB antibodies and uses thereof
    Article Snippet: Data from the ELISA were analyzed using the XY plotting function and 4-Parameter Logistic (4PL) linear regression function in GraphPad Prism software to determine the amount of free chimeric M10 or chimeric M4 present at each time point after dosing.

    Article Title: Expanded genome and proteome reallocation in a novel, robust Bacillus coagulans strain capable of utilizing pentose and hexose sugars
    Article Snippet: Optimal growth temperatures on various sugars were determined by fitting maximum growth rate versus temperature with a non-linear model (continuous hinge function, segmental regression lines with gentle connection, least squares fit) using GraphPad Prism v10.2.3.

    Article Title: In Vivo ; In Vitro Interaction of Silver Nanoparticles with Leucine Aminopeptidase from Human and Plasmodium falciparum .
    Article Snippet: There is increasing requirement for the development of new drug protocols against malaria, a fatal disease caused by the lethal parasite Plasmodium falciparum.. Leucine aminopeptidase (PfLAP) of Plasmodium falciparum, is being pursued as a promising target for the discovery of novel antimalarials.. The effects of silver nanoparticles (AgNPs) against P. falciparum leucine amino-peptidase (PfLAP) and the human homolog (HsLAP) were compared.

    Article Title: New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity.
    Article Snippet: Please cite this article as: C. Manera, A.M. Malfitano, T. Parkkari, V. Lucchesi, S. Carpi, F. Stefano, S. Bertini, C. Laezza, A. Ligresti, G. Saccomanni, J.R. Savinainen, E. Ciaglia, S. Pisanti, P. Gazzerro, V. Di Marzo, P. Nieri, M. Macchia, M. Bifulco, New quinoloneand 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity, European Journal of Medicinal Chemistry (2015), doi: 10.1016/j.ejmech.2015.04.034.

    Article Title: Transmitter self-regulation by extracellular glutamate in fresh human cortical slices.
    Article Snippet: Glutamate is thought to be the most important excitatory neurotransmitter in the CNS, while glutamine predominantly serves as a precursor and metabolite in the glutamate–glutamine cycle.. To verify the interaction between intrinsic extracellular glutamate, y-aminobutyric acid (GABA) levels and glial glutamine outflow in human tissue, fresh brain slices from human frontal cortex were incubated in superfusion chambers in vitro.. Human neocortical tissue was obtained during surgical treatment of subcortical brain tumors.

    Article Title: Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity
    Article Snippet: The concentration producing 50% inhibition (IC50) was determined by non-linear regression function PRISM 6, Version 6.01 (GraphPad Prism6 ® Software Inc., La Jolla, CA, United States).

    Article Title: The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation
    Article Snippet: ATPase reactions were carried out with increasing concentrations of ATP (12.5, 25, 50, 100, 200, 400, 800, 1600 μM) and ATPase rates were analyzed with the Michaelis-Menten non-linear regression function in GraphPad Prism.

    Concentration Assay:

    Article Title: N-halamine polyelectrolytes used for preparation of antibacterial polypropylene nonwoven fabrics and study on their basal cytotoxicity and mutagenicity
    Article Snippet: Polymeric N-halamine precursors, cationic poly((3-acrylamidopropyl) trimethylammonium chloride) (CHP) and anionic poly(2-acrylamido-2-methylpropane sulfonic acid sodium salt) (AHP), were synthesized and coated onto polypropylene nonwoven fabrics via eco-friendly dipping and spraying methods.. The successful coatings were characterized by EDS analysis.. After exposure to diluted sodium hypochlorite solution, the coatings became biocidal.

    Article Title: Anti-complement factor BB antibodies and uses thereof
    Article Snippet: Data from the ELISA were analyzed using the XY plotting function and 4-Parameter Logistic (4PL) linear regression function in GraphPad Prism software to determine the amount of free chimeric M10 or chimeric M4 present at each time point after dosing.

    Article Title: Expanded genome and proteome reallocation in a novel, robust Bacillus coagulans strain capable of utilizing pentose and hexose sugars
    Article Snippet: Optimal growth temperatures on various sugars were determined by fitting maximum growth rate versus temperature with a non-linear model (continuous hinge function, segmental regression lines with gentle connection, least squares fit) using GraphPad Prism v10.2.3.

    Article Title: In Vivo ; In Vitro Interaction of Silver Nanoparticles with Leucine Aminopeptidase from Human and Plasmodium falciparum .
    Article Snippet: There is increasing requirement for the development of new drug protocols against malaria, a fatal disease caused by the lethal parasite Plasmodium falciparum.. Leucine aminopeptidase (PfLAP) of Plasmodium falciparum, is being pursued as a promising target for the discovery of novel antimalarials.. The effects of silver nanoparticles (AgNPs) against P. falciparum leucine amino-peptidase (PfLAP) and the human homolog (HsLAP) were compared.

    Article Title: New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity.
    Article Snippet: Please cite this article as: C. Manera, A.M. Malfitano, T. Parkkari, V. Lucchesi, S. Carpi, F. Stefano, S. Bertini, C. Laezza, A. Ligresti, G. Saccomanni, J.R. Savinainen, E. Ciaglia, S. Pisanti, P. Gazzerro, V. Di Marzo, P. Nieri, M. Macchia, M. Bifulco, New quinoloneand 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity, European Journal of Medicinal Chemistry (2015), doi: 10.1016/j.ejmech.2015.04.034.

    Article Title: Transmitter self-regulation by extracellular glutamate in fresh human cortical slices.
    Article Snippet: Glutamate is thought to be the most important excitatory neurotransmitter in the CNS, while glutamine predominantly serves as a precursor and metabolite in the glutamate–glutamine cycle.. To verify the interaction between intrinsic extracellular glutamate, y-aminobutyric acid (GABA) levels and glial glutamine outflow in human tissue, fresh brain slices from human frontal cortex were incubated in superfusion chambers in vitro.. Human neocortical tissue was obtained during surgical treatment of subcortical brain tumors.

    Article Title: Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity
    Article Snippet: The concentration producing 50% inhibition (IC50) was determined by non-linear regression function PRISM 6, Version 6.01 (GraphPad Prism6 ® Software Inc., La Jolla, CA, United States).

    Article Title: The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation
    Article Snippet: ATPase reactions were carried out with increasing concentrations of ATP (12.5, 25, 50, 100, 200, 400, 800, 1600 μM) and ATPase rates were analyzed with the Michaelis-Menten non-linear regression function in GraphPad Prism.

    Inhibition:

    Article Title: N-halamine polyelectrolytes used for preparation of antibacterial polypropylene nonwoven fabrics and study on their basal cytotoxicity and mutagenicity
    Article Snippet: Polymeric N-halamine precursors, cationic poly((3-acrylamidopropyl) trimethylammonium chloride) (CHP) and anionic poly(2-acrylamido-2-methylpropane sulfonic acid sodium salt) (AHP), were synthesized and coated onto polypropylene nonwoven fabrics via eco-friendly dipping and spraying methods.. The successful coatings were characterized by EDS analysis.. After exposure to diluted sodium hypochlorite solution, the coatings became biocidal.

    Article Title: Anti-complement factor BB antibodies and uses thereof
    Article Snippet: Data from the ELISA were analyzed using the XY plotting function and 4-Parameter Logistic (4PL) linear regression function in GraphPad Prism software to determine the amount of free chimeric M10 or chimeric M4 present at each time point after dosing.

    Article Title: Expanded genome and proteome reallocation in a novel, robust Bacillus coagulans strain capable of utilizing pentose and hexose sugars
    Article Snippet: Optimal growth temperatures on various sugars were determined by fitting maximum growth rate versus temperature with a non-linear model (continuous hinge function, segmental regression lines with gentle connection, least squares fit) using GraphPad Prism v10.2.3.

    Article Title: In Vivo ; In Vitro Interaction of Silver Nanoparticles with Leucine Aminopeptidase from Human and Plasmodium falciparum .
    Article Snippet: There is increasing requirement for the development of new drug protocols against malaria, a fatal disease caused by the lethal parasite Plasmodium falciparum.. Leucine aminopeptidase (PfLAP) of Plasmodium falciparum, is being pursued as a promising target for the discovery of novel antimalarials.. The effects of silver nanoparticles (AgNPs) against P. falciparum leucine amino-peptidase (PfLAP) and the human homolog (HsLAP) were compared.

    Article Title: New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity.
    Article Snippet: Please cite this article as: C. Manera, A.M. Malfitano, T. Parkkari, V. Lucchesi, S. Carpi, F. Stefano, S. Bertini, C. Laezza, A. Ligresti, G. Saccomanni, J.R. Savinainen, E. Ciaglia, S. Pisanti, P. Gazzerro, V. Di Marzo, P. Nieri, M. Macchia, M. Bifulco, New quinoloneand 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity, European Journal of Medicinal Chemistry (2015), doi: 10.1016/j.ejmech.2015.04.034.

    Article Title: Transmitter self-regulation by extracellular glutamate in fresh human cortical slices.
    Article Snippet: Glutamate is thought to be the most important excitatory neurotransmitter in the CNS, while glutamine predominantly serves as a precursor and metabolite in the glutamate–glutamine cycle.. To verify the interaction between intrinsic extracellular glutamate, y-aminobutyric acid (GABA) levels and glial glutamine outflow in human tissue, fresh brain slices from human frontal cortex were incubated in superfusion chambers in vitro.. Human neocortical tissue was obtained during surgical treatment of subcortical brain tumors.

    Article Title: Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity
    Article Snippet: The concentration producing 50% inhibition (IC50) was determined by non-linear regression function PRISM 6, Version 6.01 (GraphPad Prism6 ® Software Inc., La Jolla, CA, United States).

    Article Title: The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation
    Article Snippet: ATPase reactions were carried out with increasing concentrations of ATP (12.5, 25, 50, 100, 200, 400, 800, 1600 μM) and ATPase rates were analyzed with the Michaelis-Menten non-linear regression function in GraphPad Prism.



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